Potential sources of error during virus thermal inactivation
نویسندگان
چکیده
منابع مشابه
Thermal inactivation of bovine immunodeficiency virus.
Cell-associated bovine immunodeficiency virus (BIV) and cell-free BIV were subjected to increasing temperatures, including pasteurization conditions. To determine the effect of heat treatment on BIV viability, reverse transcriptase activity and infectivity of the heat-treated virus were assessed. BIV was inactivated by heating to 47 degrees C for 30 min and by low- and high-temperature pasteuri...
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In recent years, considerable interest has been manifested in the thermal inactivation of animal viruses (Friedman and De Berry, 1959; LehmannGrube and Syverton, 1959; Youngner, 1957; Woese, 1960). Apart from the practical aspects, studies of the temperature sensitivity of virus particles offer a natural step in the analysis of their physicochemical properties (Gard and Maal0e, 1959) and, as su...
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The thermal stability of Newcastle disease virus has been characterized in terms of the rate constants for inactivation of hemagglutinating activity (HA), neuraminidase activity (NA), and infectivity. Inactivation of HA results in the concomitant loss of NA. Infectivity, however, is much more thermolabile. Disintegration of the virus particle is not responsible for the identical rate constants ...
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ژورنال
عنوان ژورنال: Applied and Environmental Microbiology
سال: 1978
ISSN: 0099-2240,1098-5336
DOI: 10.1128/aem.36.3.432-437.1978